The negative: Knowing what doesn’t work, leads to a) avoiding it and b) try something else which might also not work (negative loop).
The positive: Knowing what works, leads to doing it.
(Knowing what works can be found out by via negativa, however only by getting out of the negative loop of knowing what doesn’t work)
The pessimist: “It won’t work”, leads to not trying at all, i.e. remaining at the baseline / status quo (downside protection).
The optimist: “It might work”, leads to trial and error with a) downside protection (remaining at the baseline / status quo if it doesn’t work) but also b) upside potential (happy if it works).
Implication: Be an optimist focused on the positive.